The SARS-CoV-2 receptor, ACE-2, is expressed on many different cell types: implications for ACE-inhibitor- and angiotensin II receptor blocker-based cardiovascular therapies | SpringerLink
What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID-19? The experts explain
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications - ScienceDirect
The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19: Molecular Therapy - Methods & Clinical Development
Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients | eLife
ACE inhibitors, angiotensin receptor blockers and endothelial injury in COVID‐19 - Tetlow - 2021 - Journal of Internal Medicine - Wiley Online Library
IJMS | Free Full-Text | ACE2 and Innate Immunity in the Regulation of SARS-CoV-2-Induced Acute Lung Injury: A Review
SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy - eBioMedicine
The effect of renin–angiotensin–aldosterone system inhibitors on organ-specific ace2 expression in zebrafish and its implications for COVID-19 | Scientific Reports
Frontiers | Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19
Frontiers | ACE2, Much More Than Just a Receptor for SARS-COV-2
Clinical Implications of SARS-CoV-2 Interaction With Renin Angiotensin System: JACC Review Topic of the Week | Journal of the American College of Cardiology
SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications - ScienceDirect
Angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers in COVID-19 - The Centre for Evidence-Based Medicine
ACE2 as a potential therapeutic target for pandemic COVID-19 - RSC Advances (RSC Publishing) DOI:10.1039/D0RA08228G
Interactions of coronaviruses with ACE2, angiotensin II, and RAS inhibitors—lessons from available evidence and insights into COVID-19 | Hypertension Research
IJMS | Free Full-Text | COVID-19 and RAS: Unravelling an Unclear Relationship
COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection
Frontiers | Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19
Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure | Circulation Research
Pathogens | Free Full-Text | The Impact of Angiotensin-Converting Enzyme 2 ( ACE2) Expression on the Incidence and Severity of COVID-19 Infection
Controversies of renin–angiotensin system inhibition during the COVID-19 pandemic | Nature Reviews Nephrology
Frontiers | Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis?
